https://yang.chem.ucsb.edu/research daily 0.75 2026-02-10 https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/1591814824743-EAFLMU0UFZUOI14GRSTS/P450_heme.png Research https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/1591814864159-CUFHII62QAU87SCA1PA8/TrpB-PLP_2.png Research https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/ba76a1fe-8598-4a7e-b9ff-c15f84aa4098/de+novo+design.png Research https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/1591815284948-UT2U691PSS4ZKOQS86N5/conductive+protein+wire_2.png Research https://yang.chem.ucsb.edu/yang daily 0.75 2026-01-20 https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/0bf2dcc2-ba59-4934-974d-2a03c4f12487/20250519_HHMI_Yang_19.png About Yang https://yang.chem.ucsb.edu/contact daily 0.75 2026-01-06 https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/1594836013480-NKH7U0P7QBA38651OHDH/Storke_Tower_030.jpg Contact - Contact Prof. Yang Yang Department of Chemistry and Biochemistry University of California, Santa Barbara Santa Barbara, CA 93106 Office: Chem 1161C (note that I moved back to Chem 1161C from PSBN 2512) Email: yang@chem.ucsb.edu Office Phone: (805) 893-2134 Lab: PSBN 2608, PSBN 2624, Chem 2102, Chem 2104, Chem 2106, Chem 2108 and Chem 2126 Chem 2135 (Instrumentation) Student Office: PSBN 2612, PSBN 2614, PSBN 2618, Chem 2111 and Chem 2134 https://yang.chem.ucsb.edu/home daily 1.0 2026-03-04 https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/030c24dd-5708-49b0-b91a-074aaee678dc/research+highlight.png https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/e2a8a903-70e6-4ba2-901b-bbf3bd77584e/TOC.jpg https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/05303b2e-daf1-4d06-9b31-9631525ec09f/TOC_mechanism.png https://yang.chem.ucsb.edu/equipment daily 0.75 2024-12-04 https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/ba919eed-2cf3-4796-b270-c4e4c43e9d1c/Coy+chamber+1.jpg Equipment Coy Chamber 1 for Photobiocatalysis (PSBN 2624) The Coy anaerobic chamber uses Pd catalysts to strip O2 with H2, producing H2O. It allows us to handle air-sensitive protein samples and set up biocatalytic reactions using air-sensitive enzymes. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/e97b0616-1d5f-49e9-94fe-b78220f7e0a2/Coy+chamber+2.jpg Equipment - Make it stand out Coy Chamber 2 for Metalloredox Biocatalysis (PSBN 2608) This second Coy anaerobic chamber was purchased in 2023 for metalloenzyme projects. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/1598377903585-9JWSK9YA13BKHTS1LNRR/class+II+biosafety+cabinet.jpg Equipment Class II Biosafety Cabinet 1 (PSBN 2624) We have two class II biosafety cabinets in our labs. These BSCs enable convenient and safe handling of various types of microorganisms. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/889825c1-f410-4154-a25e-42f210d57b16/BSC_2.jpg Equipment - Make it stand out Class II Biosafety Cabinet 2 (PSBN 2624) This is the second BSC we have in our lab. This BSC is also located in PSBN 2624. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/1598414078050-BN22LDF7UN7J4GY7BNPK/Glovebox.jpg Equipment Glovebox 1 (PSBN 2608) The N2 filled glovebox allows us to set up air- and moisture-sensitive reactions conveniently. This glovebox is also used to store air- and/or moisture sensitive reagents. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/efe6d797-6942-4cf7-9543-6ba65dfd7c87/glovebox_2.jpg Equipment - Make it stand out Glovebox 2 (Chem 2108) https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/1598414298087-B5HQJSC2HV0ZE9MYNACJ/Shimadzu+HPLC.jpg Equipment Normal-Phase HPLC 1 (PSBN 2624) We have a Shimadzu LC-2040C equipped with a photodiode array (PDA) detector as one of the key analytical workhorses. This HPLC is currently configured as a normal phase HPLC for chiral analysis. Chiral columns from Daicel Chiral Technologies, including IA, IB, IC, IG, IF, IH, OD-H and OJ-H, are commonly used for chiral analysis. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/0af9c880-0b75-4f99-874a-3f49f07c54db/HPLC_reverse+phase.jpg Equipment - Make it stand out Reverse-Phase HPLC 1 (PSBN 2608) Agilent HPLC Infinity 1200. This HPLC can only be used for reverse-phase HPLC analysis. Do not reconfigure it for normal-phase analysis. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/c18281bf-6583-481a-b160-228c3bf33e50/2022-07-08+00.10.03.jpg Equipment - Make it stand out Normal-Phase HPLC 2 (PSBN 2608) Another Shimadzu HPLC equipped with a PDA detector, an autosampler, a column oven and binary pumps. This HPLC is currently configured as a normal phase HPLC. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/13cacaec-476c-4f52-8fd9-e50a33d34e47/HPLC3.jpg Equipment - Make it stand out Normal-Phase HPLC 3 (PSBN 2624) This is the third Shimadzu HPLC we have for normal-phase HPLC analysis. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/1610216169124-BGFJZ30IB3COJN4JKYZM/2021-01-09+09.55.47.jpg Equipment Reverse-Phase HPLC-MS (PSBN 2624) This Shimadzu LCMS-2020 allows for the convenient analysis of aqueous samples and ionizable compounds (e.g., amino acids, nitrogen-containing compounds). https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/d6bbd7b8-706e-4d59-9bbb-27ba4cc73229/UPLC-MS.jpg Equipment - Make it stand out Reverse-Phase UPLC-MS (PSBN 2608) This Shimadzu UPLC MS-2030 was recently acquired to allow for higher throughput analysis. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/1610215698939-SD3DX8WOUMDRPQLTPHJ5/2021-01-09+09.55.06.jpg Equipment GC-MS (PSBN 2608) This Shimadzu GCMS-QP2020 is our primary workhorse for the analysis of both chemical and biocatalytic reactions. An in-house GC-MS allows us to rapidly analyze crude reaction mixtures and quantify the yield and conversion of chemical reactions. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/1610215542298-V8WCLUSH47RZMF7CDYDY/2021-01-09+09.54.38.jpg Equipment GC (PSBN 2608) We have a Shimadzu GC-2030 equipped with chiral GC columns. Chiral GC is routinely used in our laboratory for the high-throughput analysis of biocatalytic reactions. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/1598414470578-WKNJKY179XAXVBMHHWYD/UV-Vis.jpg Equipment UV-Vis Spectrophotometer (PSBN 2624) We have a Shimadzu UV-1800 spectrophotometer. This UV-1800 is commonly used for the characterization of protein samples. In addition, many proteins bearing an organic or organometallic coenzyme display characteristic UV-Vis signals. The UV-Vis spectrophotometer permits both qualitative and quantitative analysis of protein samples of interest. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/0f20d03f-473b-4f9d-a9bf-b9bef10f35f5/IR+spectrophotomer.jpg Equipment - Make it stand out IR Spectrometer (PSBN 2608) We have a Thermo IR spectrometer for IR data collection routinely required by organic chemistry journals. This IR spectrometer was generously donated to us by Prof. Lipshutz. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/ff04e3be-6dab-4236-82a3-512bda43018a/polarimeter.jpg Equipment - Make it stand out Polarimeter This polarimeter allows the measurement of specific rotations of chiral compounds. This polarimeter is co-purchased and shared between our lab and the Hai lab. Please use this polarimeter to measure the specific rotation of your enantioenriched compound if you make >= 10 mg of it. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/1610216359352-7PDR0R262FBPS4UX23VD/2021-01-09+09.56.57.jpg Equipment AKTA Protein Purifier 1 (PSBN 2624) We have an AKTA Start for automated protein purification. This simple AKTA models allows for affinity chromatography and ion exchange chromatography to be done efficiently. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/7438e523-1325-48d6-ae82-3361fe97206b/AKTA.jpg Equipment - Make it stand out AKTA Protein Purifier 2 (PSBN 2624) In 2023, we purchased another AKTA Start to allow for simultaneous protein purification to be conveniently carried out in our group. Both AKTAs are housed in a Deli fridge at 4 C. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/1611016899368-830YSOX16AP4G20T9AYQ/2021-01-14+22.01.00.jpg Equipment Biotage Isolera (PSBN 2608) This Biotage Isolera allows for automated column chromatography on various scales. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/130314f8-d379-4501-8e12-07ec26f47c70/Gel+Imager.jpg Equipment - Make it stand out Protein and DNA Gel Imager (PSBN 2608) This Bio-Rad Gel Doc EZ Imager with its associated software allows us to analyze both protein and DNA gels quantitatively. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/1610216514233-MHCBIA9FY08HE2EKEIP5/2021-01-09+09.56.39.jpg Equipment https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/6e480e7e-68b4-4732-9dd7-6741e2d2288f/thermocycler.jpg Equipment - Make it stand out Thermocyclers (PSBN 2624) We have three Bio-Rad T100 thermocyclers for molecular biology. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/f90b0161-892b-45fe-9b64-d8d48f28c4f4/2022-07-08+00.08.33.jpg Equipment - Make it stand out DNA Gel Station (PSBN 2624) DNA agarose gel and protein SDS-PAGE gel analysis can be done conveniently in our lab. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/6cc1bfab-e2a6-4b51-8a8b-6217da4d2b43/2022-07-08+00.08.52.jpg Equipment - Make it stand out Protein Gel Station (PSBN 2624) DNA agarose gel and protein SDS-PAGE gel analysis can be done conveniently in our lab. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/1610216590487-T84F1PNNZPH4KDQV62BF/2021-01-09+09.56.17.jpg Equipment New Brunswick Innova 44R Shakers 1,2 and 3 (PSBN 2624) We have three New Brunswick Innova 44R shakers to grow microorganisms and express proteins of interest. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/d17d2b46-dfe2-439a-80da-b61c9f2578d6/shakers.jpg Equipment - Make it stand out New Brunswick Innova 44R Shakers 6 and 7 (Chem 2143) https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/ab420c2a-cbef-4724-8ac7-f5db8c376853/Tabletop+5910Ri.jpg Equipment - Make it stand out Eppendorf 5910Ri Tabletop Centrifuge 1 (PSBN 2624) We have two Eppendorf tabletop centrifuge (5910R and 5910Ri) equipped with a universal platform for cell culture work. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/01bdb5c7-ece7-4e04-8e6b-acefab890a8f/2022-07-08+00.11.09.jpg Equipment - Make it stand out New Brunswick Innova 42R Shakers 4 and 5 (PSBN 2624) We have two Innova 42R shakers to grow microorganisms and express proteins of interest. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/69d05cc3-a870-45cb-a2af-bcef6a7e27ae/Tabletop+5910R.jpg Equipment - Make it stand out Eppendorf 5910R Tabletop Centrifuge 2 (PSBN 2624) We have two Eppendorf tabletop centrifuge (5910R and 5910Ri) equipped with a universal platform for cell culture work. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/a730189a-3409-44f3-925a-da4104aec4f5/Microcentrifuge+5424R.jpg Equipment - Make it stand out Eppendorf Microcentrifuge 5424R (PSBN 2624) https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/1610216702286-EXE2NXW7UNU6G1991RJ4/2021-01-09+09.58.03.jpg Equipment Eppendorf F570h ULT Freezer 1 (PSBN 2624) This Eppendorf F570h ultra low temperature freezer is used to store microorganisms and protein samples. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/22fbb6f6-8933-477b-8fa2-197cb5f0ace6/microcentrifuges.jpg Equipment - Make it stand out Eppendorf Microcentrifuges 5425 and 5418 (PSBN 2624) https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/6ea060cc-948a-49e1-910f-00ad7ce91998/Thermo+TSX-700+ULT+freezer.jpg Equipment - Make it stand out Thermo Scientific TSX-700 ULT Freezer 2 (PSBN 2624) This second Thermo TSX-700 ultra low temperature freezer is purchased in 2023 for biological sample storage. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/2ab6c747-e7a9-46be-a24a-ac64c5ecbff4/Floor+centrifuge.jpg Equipment - Make it stand out Lynx Superspeed Centrifuge 1 (PSBN 2624) This Thermo Scientific Lynx superspeed centrifuge is routinely used in protein purification. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/4b49aa8d-e504-42cd-9643-1bd55522e71b/Sonicator.jpg Equipment - Make it stand out Sonicators (PSBN 2608) We have 4 QSonica Q500 sonicators for cell lysis with various applications. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/d6bc38e3-6983-4ecd-93c9-60c299eac364/MilliQ_pHmeter.jpg Equipment - Make it stand out Milli-Q Water System and pHmeter (PSBN 2624) Our Milli-Q water system allows doubly-deionized water to be prepared. pHmeter is routinely used to make buffers for biochemistry. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/771d9095-0882-40f5-9f55-4941e75b2c82/Kessil+LED.jpg Equipment - Make it stand out Kessil LED Lamps for Photobiocatalysis https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/b5898fed-ceaa-487c-93b7-67a2423d0db6/photoreactor.jpg Equipment - Make it stand out Photoreactors for Photobiocatalysis https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/838899e7-0bd5-429d-8a50-786f8c2139f3/Lynx+centrifuge.jpg Equipment - Make it stand out Lynx Superspeed Centrifuge 2 (PSBN 2608) This Thermo Scientific Lynx superspeed centrifuge will be used for bacterial cell harvesting. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/68c32e7e-6990-4f25-bdeb-004d575873f8/Lyophilizer.jpg Equipment - Make it stand out Lyophilizer (PSBN 2624) This lyophilizer is used to freeze-dry protein samples, amino acids, and other hydrophilic compounds https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/5ba0b365-eee7-4d56-983f-a7eb74317e15/Nanodrop.jpg Equipment - Make it stand out NanoDrop UV-Vis Spectrophotometer This NanoDrop is used for routine DNA and protein sample analysis. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/88800a69-9805-413b-9d88-e0300cbfce7f/ODmeter.jpg Equipment - Make it stand out ODmeter (PSBN 2624) ODmeter is routinely used to measure the cell density in cell culture work. https://yang.chem.ucsb.edu/current-members daily 0.75 2025-11-19 https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/61ee185b-ee15-455a-8b6e-50a50b11bb3e/Zhiyu.jpg https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/855e90c8-6bce-486e-bfd4-f7eae46b319d/image_6483441.jpg https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/1c820d3a-327b-4bb4-a35f-8efad1f01249/Zheng+Zhang.jpeg https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/7df77a0e-6bd3-4d16-baa3-f4af95758a91/Jun+Zhou.jpg https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/316df746-ccbb-477e-a277-a6282a36d71f/2D75DB94-5C04-4A88-9A87-4A0948F7FE05.jpeg https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/89c23500-74f9-4df1-ace1-050a9ef7c33c/Ken+Lin.jpg https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/674dc2ac-d4e8-4217-b775-7b365342e4db/Benjamin+Krohn-Hansen.jpeg https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/7296fec7-7dbb-44cf-97b6-ba0fedf9a26b/Angel+Roman.jpeg https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/a6f7218a-9ac9-46c0-8ff3-81c16d118f77/Michael+Bratslavsky.jpeg https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/25bbb113-4914-404b-834b-3338bf0e5903/Lydia+Cumming.jpg https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/07fb9044-5fd4-403f-b3d6-b0c188c25668/Jasper+Chen.jpg https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/6b619151-25cb-4ed2-b40d-fc821f8efede/Wei+Huang.jpg https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/b64c71ad-685a-4d79-8c4f-f47f8ca87482/2022-06-04+10.05.08.jpg https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/5cdd6677-3f25-465b-b50c-5d714495a75e/Huanan+Wang.jpg https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/7383fe31-4610-44a2-a87f-545fa2cfd005/Qingdong+Hu.jpg https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/125f71ca-28bb-4d34-9702-b8f2d7bc3776/Chen+Zhang.jpg https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/1c8d314f-0c81-418b-8ff4-ea3ea7eec6a1/Liupeng+Zhao.jpg https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/5fe53b32-e52e-4eab-8854-6119ace1d323/Xiaowang+Chen.jpg https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/0cc19e9f-e20a-4ebe-84e2-ccf55c91b980/Photo-An+Liu.jpg https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/86690d61-7d87-4aea-9574-0bd4e69de1e7/Cheng+Sheng.jpg https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/6102ebbf-697e-4069-bef9-b9794acfbffa/Qi+Zhang.jpg https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/9edd45e2-664d-4828-bba6-47c444c3ad0f/Tim+Ke.jpg https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/4c8546be-1acb-45ba-a595-84cf3477451a/Cangxin+Zheng.jpg https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/573e4b66-e9b1-467f-9ce6-1e99c2c66b8b/Hongda_photo.jpg https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/14977fa4-5cf1-4f09-a2d3-fe9d5ff47ea0/Long+Dinh.png https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/7cdcf0b4-1211-43c8-80c4-cd5286ce3969/xuejiao+lyu.jpg https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/d747f282-b785-42a6-b914-a355eba3d661/Yu+Tian.jpg https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/47060f7d-1b57-4635-b49b-7d0e61888de2/Zhiyang+Li.jpg https://yang.chem.ucsb.edu/alumni daily 0.75 2025-02-07 https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/a0b2db18-dc60-4891-90c6-18da38f73a31/Yunlong+Zhao.jpg Alumni - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/85125ea6-272f-4ca0-a0a0-6f040bdfe417/Qi+Zhou.jpg Alumni - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/c6596e31-1789-42bf-a211-ba4d23d5fc9f/Shuyun+Ju.jpg Alumni - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/46ed452b-194a-4c4e-80b8-8b88d113b119/Wenzhen+Fu.jpg Alumni - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://yang.chem.ucsb.edu/publications daily 0.75 2026-03-27 https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/10e922ea-3388-49ce-a338-dd28cac43c07/TOC.png Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/20d1dcb7-c6f0-405e-8883-f13a7978e325/TOC.png Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/5cc0a085-92b7-4596-9cf4-c45516f2d9d7/TOCv2.png Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/cba654c8-61a6-454e-80af-7b51a0f2c03a/TOC.jpg Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/7fc77aa5-8071-4325-af73-3295da276f96/TOC-v5.jpg Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/63180df2-de8d-4656-b5af-ddefc7892244/TOC.png Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/2e408508-b5f9-4205-80c9-818582ab0195/TOC.jpg Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/8033ee41-5a32-4101-b307-9a435600e61a/Fig1.jpg Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/f7ddc8c8-3e7d-4ee3-b98c-c07b8ea70727/TOC.png Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/33189418-f267-42e9-b077-a479d16a63f6/TOC3.jpg Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/56265760-0758-451e-99d7-58c571c34dbb/TOC+website.png Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/40469b66-d163-4b35-b3bf-f4573919e88e/TOC.jpg Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/7e3ab213-68c8-43c2-8bb9-98362b8e327d/Website+TOC.png Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/91bb39c0-e6e3-40ac-bfc4-6f6942577653/TOC.png Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/6f324f07-d708-4e76-9026-8812fd670c3f/TOC.jpg Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/83720ea4-43ad-4abf-80d7-748d026c0547/MODIFY.png Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/229b8b9e-9ab1-43ee-966a-2e726312085e/TOC_website.png Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/4ee4de99-5a40-4c3e-8808-4c6a73acf354/JACS+cover.jpg Publications - Make it stand out About the Cover: Pyridoxal 5´-phosphate (PLP) enzymes are essential biosynthetic machinery underlying amino acid metabolism. Now, through visible light induced free radical initiation, PLP-dependent threonine aldolases are repurposed to catalyze asymmetric intermolecular free radical coupling reactions for amino acid synthesis. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/e897ae67-fbfa-4008-9a4c-24dc595608df/EnzyGen.png Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/70234e78-9512-42e3-bd14-0a74d0e7afdf/webpage+TOC.png Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/fc2f05d3-a5ed-4063-8b56-306ded3879e8/TOC1.png Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/2375ed99-c837-4564-b222-082fc3458e85/Fig1_new.png Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/781316f6-59dc-4e59-a314-9a2b5edd1546/Twitter.png Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/3a2ddee6-753c-4764-8fef-1f629acd7500/TOC+website.png Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/7f669871-b82e-4656-ac15-7fa7c200b002/51CNqFyFMML._AC_UF1000%2C1000_QL80_.jpg Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/9e08974c-2cb6-4589-b7ea-8c7c460cd49d/TOC.png Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/6516e51f-6871-4f89-8de6-9cc0432253b3/TOC.png Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/8f7e21a1-6088-47bd-abc7-0d9d03d3052a/Fig1_Final_v2.png Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/698e805a-9fad-4700-9894-0dfad07b91be/cover+art.png Publications - Make it stand out Stereocontrolled free-radical-mediated reactions are notoriously challenging. Now, Peng Liu, Yang Yang and colleagues report the directed evolution of cytochrome P450 enzymes for the asymmetric radical cyclization of α-haloesters to arenes. Complementary P450 radical cyclases are obtained allowing access to both enantiomeric products. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/2b3e7933-4bf0-4096-9b2f-36f3e6a1658d/TOC.png Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/793767f9-37ad-4dab-9aab-d9663d0e5b4a/toc_YY.png Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/08133fc7-6a4e-471a-953f-4a453fb13222/jacsat_v144i025.jpeg Publications - Make it stand out About the Cover: A combined computational and experimental study reveals that, contrary to previously hypothesized enantioinduction mechanisms, the radical rebound step is enantioselectivity-determining under the Curtin–Hammett conditions, whereas the preceding HAT step is only moderately stereoselective. This study highlights an unusual enantioinduction mechanism in metalloenzyme-catalyzed asymmetric transformations involving radical intermediates. Cover art by Binh Khanh Mai. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/72e37902-ac20-402d-865c-682238035d56/Fig1A.png Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/1614682128122-9T2JGK98HGL9JJKOFQNU/achre4_v054i005.jpg Publications About the Cover: The catalytic repertoire of heme proteins covers an astonishing range of reactions in nature. Now, enabled by directed evolution, cytochromes P450 and other heme proteins have been repurposed to catalyze a large and growing set of carbene and nitrene transfer reactions previously unknown in biology. Cover art by Lei Chen. See article by Yang Yang and Frances H. Arnold (DOI: 10.1021/acs.accounts.0c00591). https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/1591821086731-3CRODIWJTY2TYROLS09K/P450_TOC.png Publications https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/1591827971645-J34JC7EJCNKZM224QF4S/ja-2017-07373c_0006.jpeg Publications https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/1591831780001-STMUYH6UHQG17PCFQ1N9/imine_2.png Publications https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/1591829293491-GNRUBKFNTKOPZ09HF1L6/allene-imine-3.png Publications https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/1591831478767-Z8B0NN0R45Z7SFD6DIIU/ketone_2.png Publications https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/1591827659603-ZLPP80JNWJ5B9IUHHJY9/Picture1.png Publications https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/1591830563846-7E5LK3B1SFM9WRTMSD3O/hydroamination_2.png Publications https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/1591828177403-QGRKTOGMJGQQJXSDWKUW/cs-2015-004438_0016.jpeg Publications https://images.squarespace-cdn.com/content/v1/5ee123ab4b96eb12820de1aa/1591827770934-4LRJ04DZOP34SI8Q5HGR/mcontent+%283%29.jpg Publications https://yang.chem.ucsb.edu/group-jobs daily 0.75 2023-04-29 https://yang.chem.ucsb.edu/openings daily 0.75 2023-04-29 https://yang.chem.ucsb.edu/patents daily 0.75 2023-07-27 https://yang.chem.ucsb.edu/home-1 daily 0.75 2025-06-10 https://images.squarespace-cdn.com/content/v1/5ce30eac883b8e00019e90b0/1559258266997-O8BLKTFSZTEW874XPZA5/Aro%2BHa_0507.jpg Home https://images.squarespace-cdn.com/content/v1/5ce30eac883b8e00019e90b0/1559258266730-OSGHXQ1AYMH9GA2ZAWQY/Aro%2BHa_0029.jpg Home https://images.squarespace-cdn.com/content/v1/5ce30eac883b8e00019e90b0/1559258266916-GTV1TV9RLVORI7QBQIHL/EmptyName-30.jpg Home https://images.squarespace-cdn.com/content/v1/5ce30eac883b8e00019e90b0/1559258267329-WWZONV8SJCOWI01JU2TX/ishimoto%2B3.jpg Home